One-Pot Synthesis of Oxime Ethers from Benzaldehyde or Acetophenone, Hydroxylamine Salt, Potassium Hydroxide, and Alkyl Halides

Chunbao Li, Hang Zhang, Yi Cui, Shuanming Zhang, Zheyuan Zhao, Michael C. K. Choi, Albert S. C. Chan

Synthetic Communications · 2003 · 21 citations · 5 references

Concepts

Abstract

Abstract Oxime ethers were synthesized in one-pot reaction from benzaldehyde or acetophenone, hydroxylamine hydrogen chloride, alkyl halides and KOH in aqueous DMSO. The reactions were completed in 15–50 min with yields in 80–96%.

References

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