Functional Characterization of YM928, a Novel Noncompetitive α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

Richard Morris, Eric Anderson, Gary Lynch et al. · Nature · 1986 · 3.6K citations

Life Sciences, Neuroscience, Pharmacology +15

Pathological Changes Induced in Cerebrocortical Neurons by Phencyclidine and Related Drugs

John W. Olney, Joann Labruyere, Madelon T. Price · Science · 1989 · 1.3K citations

Medicine, Neuroscience, Pharmacology +17

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a Neuroprotectant for Cerebral Ischemia

Malcolm J. Sheardown, Elsebet Ø. Nielsen, Anker Jón Hansen et al. · Science · 1990 · 1.1K citations

Medicine, Neuroscience, Pharmacology +16

The glutamate antagonist MK‐801 reduces focal ischemic brain damage in the rat

C. K. Park, Daniel G. Nehls, David I. Graham et al. · Annals of Neurology · 1988 · 547 citations

Medicine, Neuroscience, Pharmacology +17

MK-801, a proposed noncompetitive antagonist of excitatory amino acid neurotransmission, produces phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys.

Wouter Koek, J H Woods, Gail Winger · Journal of Pharmacology and Experimental Therapeutics · 1988 · 307 citations

Life Sciences, Neuroscience, Pharmacology +16