Angewandte Chemie International Edition · 2006 · 231 citations · 19 references
MedicineBiochemistryBiophotonicsOcular AnatomyVisual OpticsPhotoreceptor PhysiologyRetinal AnatomyCrystallographic Symmetry AnalysisPhotochemical Cycle Of RetinalPhotoreceptor BiologyRetinal Chromophore IsomerizationRetinal PhototransductionRhodopsin FunctionRhodopsin Phototransduction
A curved retinal: Difference electron-density data between the photoreceptor protein rhodopsin and its primary photoreaction intermediate bathorhodopsin have provided a crystallographic model for the cis–trans isomerization of the chromophore retinal therein during the primary process in dim-light vision (see picture; the curved polyene structure of retinal in bathorhodopsin is shown in red, while that in rhodopsin is colored green).
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Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor
Krzysztof Palczewski, Takashi Kumasaka, Tetsuya Hori et al. · Science · 2000 · 5.6K citations
Requirement of Rigid-Body Motion of Transmembrane Helices for Light Activation of Rhodopsin
David Farrens, Christian Altenbach, Ke Yang et al. · Science · 1996 · 1.2K citations
The First Step in Vision: Femtosecond Isomerization of Rhodopsin
R. W. Schoenlein, Linda A. Peteanu, R. A. Mathies et al. · Science · 1991 · 881 citations