Cuticle thickening associated with pyrethroid resistance in the major malaria vector Anopheles funestus

Abstract

Pyrethroid tolerant or resistant An. funestus females are likely to have thicker cuticles than less tolerant or susceptible females, and females generally have thicker cuticles than males. In pyrethroid resistant An. funestus, this increase in cuticle thickness is likely to have developed as an auxiliary to the primary mode of pyrethroid resistance which is based on enzyme-mediated detoxification.