Development and Validation of a New Adenosine-Independent Index of Stenosis Severity From Coronary Wave–Intensity Analysis

Sayan Sen, Javier Escaned, Iqbal Malik, Ghada Mikhail, Rodney A. Foale, Rafael Mila, Jason M. Tarkin, Ricardo Petraco, Christopher Broyd, Richard J. Jabbour,

Journal of the American College of Cardiology · 2011 · 648 citations · 18 references

DOIFull text

Open access

Abstract

Intracoronary resistance is naturally constant and minimized during the wave-free period. The instantaneous wave-free ratio calculated over this period produces a drug-free index of stenosis severity comparable to FFR. (Vasodilator Free Measure of Fractional Flow Reserve [ADVISE]; NCT01118481).

References

18