Prospective randomised trial comparing fluorouracil versus doxifluridine for the treatment of advanced colorectal cancer

Fluorinated Pyrimidines, A New Class of Tumour-Inhibitory Compounds

Charles Heidelberger, P Danneberg, Dorothy Mooren et al. · Nature · 1957 · 1.6K citations

Medicine, Medicinal Chemistry, Oncology +11

A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: a Mid-Atlantic Oncology Program Study.

J J Lokich, James D. Ahlgren, John J. Gullo et al. · Journal of Clinical Oncology · 1989 · 772 citations

Medicine, Oncology, Pharmacology +15

The modulation of fluorouracil with leucovorin in metastatic colorectal carcinoma: a prospective randomized phase III trial. Gastrointestinal Tumor Study Group.

Nicholas J. Petrelli, H. O. Douglass, L Herrera et al. · Journal of Clinical Oncology · 1989 · 557 citations

Medicine, Oncology, Pharmacology +17

A randomized trial of fluorouracil and folinic acid in patients with metastatic colorectal carcinoma.

Charles Erlichman, Shai Fine, A. Wong et al. · Journal of Clinical Oncology · 1988 · 506 citations

Pharmacy, Oncology, Pharmacotherapy +15

A prospective randomized trial of 5-fluorouracil versus 5-fluorouracil and high-dose leucovorin versus 5-fluorouracil and methotrexate in previously untreated patients with advanced colorectal carcinoma.

Nicholas J. Petrelli, L Herrera, Youcef M. Rustum et al. · Journal of Clinical Oncology · 1987 · 451 citations

Medicine, Oncology, Pharmacotherapy +15