Sesquiterpene lactone trilobolide activates production of interferon-γ and nitric oxide

Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase.

Q.W. Xie, Yumiko Kashiwabara, Carl Nathan · Journal of Biological Chemistry · 1994 · 2.2K citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Induction of nitrite/nitrate synthesis in murine macrophages by BCG infection, lymphokines, or interferon-gamma.

Dennis J. Stuehr, Michael A. Marletta · The Journal of Immunology · 1987 · 717 citations · Full text

Life Sciences, Immunology, Microbiology +15

Regulation and subcellular location of nitrogen oxide synthases in RAW264.7 macrophages.

Harald Schmidt, Timothy D. Warner, Masaki Nakane et al. · Molecular Pharmacology · 1992 · 251 citations

Life Sciences, Cell Biology, Immunology +13

Quantitative Structure−Activity Relationship of Sesquiterpene Lactones as Inhibitors of the Transcription Factor NF-κB

Bettina Siedle, Alfonso García‐Piñeres, Renato Murillo et al. · Journal of Medicinal Chemistry · 2004 · 243 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Salmonella typhimurium induces epithelial IL-8 expression via Ca2+-mediated activation of the NF-κB pathway

Andrew T. Gewirtz, Anjali Rao, Peter O. Simon et al. · Journal of Clinical Investigation · 2000 · 224 citations · Full text

Life Sciences, Immunology, Microbiology +17