Concepedia

Stereoconservative Negishi arylation and alkynylation as an efficient approach to enantiopure 2,2′-diarylated 1,1′-binaphthyls

Katarína Krascsenicsová, Peter Jomo Walla, Peter Kasák, Georg Uray, C. Oliver Kappe, Martin Putala

Chemical Communications · 2004 · 45 citations · 22 references

DOI

Concepts

Abstract

Negishi arylation and alkynylation of easily synthesized chiral 2,2'-diodo-1,1'-binaphthyl rapidly proceeds in refluxing THF utilizing controlled microwave irradiation, affording enantiopure 2,2'-diarylated 1,1'-binaphthyls in good to excellent yields.

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