Rhodium(III)‐Catalyzed Oxidative CH Coupling of <i>N</i>‐Methoxybenzamides with Aryl Boronic Acids: One‐Pot Synthesis of Phenanthridinones

Abstract

General solution: An efficient rhodium-catalyzed dual CH bond activation and cyclization of N-methoxybenzamides 1 with aryl boronic acids 2 (see scheme; Cp*=Me5C5) provides a straightforward and general approach to the phenanthridinone structure, which occurs widely in natural products and drugs. Highly regioselective CC and CN bond formation under mild conditions afforded a wide range of substituted phenanthridinones 3. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.