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Impact of POR*28 on the clinical pharmacokinetics of CYP3A phenotyping probes midazolam and erythromycin

DOI

42

Citations

36

References

2013

Year

Laure Elens, Annemieke J.M. Nieuweboer, Stephen Clarke, Kellie A. Charles, Anne‐Joy M. de Graan, Vincent Haufroid, Teun van Gelder, Ron H.J. Mathijssen, Ron H. N. van Schaik
Pharmacogenetics and Genomics

Abstract

Our data show that the POR*28 allele is associated with a lower in vivo CYP3A5 activity, but has no effects on CYP3A4-mediated erythromycin and midazolam metabolism.

References

YearCitations

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