Concepedia

Chronic Inflammation in Benign Prostate Tissue Is Associated with High-Grade Prostate Cancer in the Placebo Arm of the Prostate Cancer Prevention Trial

Bora Gürel, M. Scott Lucia, Ian M. Thompson, Phyllis J. Goodman, Catherine M. Tangen, Alan R. Kristal, Howard L. Parnes, Ashraful Hoque, Scott M. Lippman, Siobhan Sutcliffe,

Cancer Epidemiology Biomarkers & Prevention · 2014 · 231 citations · 15 references

DOIFull text

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Abstract

This study supports an etiologic link between inflammation and prostate carcinogenesis, and suggests an avenue for prevention by mitigating intraprostatic inflammation.

References

15

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Rebecca L. Siegel, Deepa Naishadham, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2013 · 11.9K citations · Full text

The Influence of Finasteride on the Development of Prostate Cancer

Ian M. Thompson, Phyllis J. Goodman, Catherine M. Tangen et al. · New England Journal of Medicine · 2003 · 2.5K citations · Full text

Asymptomatic inflammation and/or infection in benign prostatic hyperplasia

Nickel, Downey, Young et al. · British Journal of Urology · 1999 · 319 citations

Distribution of Inflammation, Pre-Malignant Lesions, Incidental Carcinoma in Histologically Confirmed Benign Prostatic Hyperplasia: A Retrospective Analysis

F. Di Silverio, Vincenzo Gentile, Anna De Matteis et al. · European Urology · 2003 · 281 citations

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Inflammation in Prostate Biopsies of Men without Prostatic Malignancy or Clinical Prostatitis

P.H.F. Schatteman, Lucien Hoekx, Jean‐Jacques Wyndaele et al. · European Urology · 2000 · 153 citations

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