REVERSAL OF DIABETES IN MICE BY XENOTRANSPLANTATION OF A BIOARTIFICIAL PANCREAS IN A PREVASCULARIZED SUBCUTANEOUS SITE1

Abstract

A successfully prevascularized subcutaneous site could be constructed by a tissue bioengineering approach. Xenotransplantation of the agarose/poly (styrene sulfonic acid) mixed gel-based bioartificial pancreas in the prevascularized subcutaneous site could reverse diabetes in mice.