Chiral Ligand Design: A Bidentate Ligand Incorporating an Acyclic Phosphaalkene

Abstract

Simply made and stable: An asymmetric phosphaalkene has been synthesized from L-valine, a readily available chiral precursor. This air-stable ligand forms a P(sp2),N(sp2) complex to iridium(I) (see scheme) and is the first example of a new class of chiral phosphorus-based ligands which are expected to possess excellent π-acceptor properties.