Effects of Intranasal Administration of Hormonal Steroids on Serum Testosterone and Spermatogenesis in Rhesus Monkey (Macaca mulatta)

T. C. Anand Kumar, A. Sehgal, Gyula Dávid, J.S. Bajaj, M.R.N. Prasad

Biology of Reproduction · 1980 · 14 citations · 7 references

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Abstract

Spraying estradiol-17β, progesterone or norethisterone intranasally in adult male rhesus monkeys (7.5–11 kg BW) at a daily dose of 30 μg/day for a period of 60 days resulted in a decrease of testicular size, arrest of spermatogenesis and a significant reduction in serum levels of testosterone. No changes were observed in the solvent-treated controls.

References

7