Pyrazolones as Building Blocks in Heterocyclic Synthesis: Synthesis of New Pyrazolopyran, Pyrazolopyridazine and Pyrazole Derivatives of Expected Antifungicidal Activity

Abstract

Abstract A series of new pyrazolone and pyrazole derivatives with expected antifungicidal activity have been prepared through the reactions 3‐phenyl‐1‐ H ‐pyrazol‐5(4 H )‐one ( 3 ) and 4‐(dimethylaminomethylene)‐3‐phenyl‐1 H ‐pyrazol‐5(4 H )‐one ( 5 ) with a variety of electrophilic reagents and nucleophilic reagents. The newly synthesized compounds were characterized by IR, 1 H NMR, 13 C NMR and mass spectral studies.