Antimicrobial Agents and Chemotherapy · 2005 · 32 citations · 23 references
Veterinary MedicineInfectious DiseasesPharmacologyDiagnostic MicrobiologyImmunology Of Infectious DiseasesMedical MicrobiologyAntimicrobial PeptidesPeptide AnalysisPeptide ChemistryAntibacterial PeptidesAntimicrobial Peptide ActivityCationic Antimicrobial PeptidesCationic PeptidesPeptide Structure-activity Relationships
The in vitro activity of six cathelicidin peptides against 25 strains of Chlamydia was investigated. SMAP-29 proved to be the most active peptide, reducing the inclusion numbers of all 10 strains of Chlamydia trachomatis tested by > or =50% at 10 microg/ml. This peptide was also active against C. pneumoniae and C. felis.
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