S100A8 enhances osteoclastic bone resorption in vitro through activation of Toll‐like receptor 4: Implications for bone destruction in murine antigen‐induced arthritis - Concepedia

Concepedia

Publication | Open Access

S100A8 enhances osteoclastic bone resorption in vitro through activation of Toll‐like receptor 4: Implications for bone destruction in murine antigen‐induced arthritis

DOI Full Paper Access

91

Citations

34

References

2011

Year

Lilyanne C. Grevers, Teun J. de Vries, Thomas Vogl, Shahla Abdollahi‐Roodsaz, A. Sloëtjes, Pieter J. M. Leenen, Johannes Roth, Vincent Everts, Wim B. van den Berg, Peter L. E. M. van Lent

Arthritis & Rheumatism

Abstract

These results demonstrate that S100A8 stimulated osteoclast formation and activity and suggest that both S100A8 and TLR-4 are important factors in mediating osteoclastic bone destruction in experimental arthritis.

References

	Year	Citations

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