The Effect of Busulfan on Body Weight, Testis Weight and MDA Enzymes in Male Rats

Abstract

Twenty Wistar male rats ranging in age from 6 to 8 weeks (20020 g) were used. Animals Were randomly allocated into two groups, control group (n=10) and experimental group (n=10) that received a single intraperitoneal injection of busulfan (50 mg/kg body weight) diluted in sesame oil as previously described (19.20). animals were housed in wire cages at 221 C under a 12-h lightdark cycle with 70% humidity and fed a standard diet and water. Animals were maintained and experiments were conducted in accordance with the Principles of