Bronchoesophageal Fistula and Fatal Hemoptysis After Bevacizumab-Containing Chemotherapy Without Radiation in Lung Cancer

Abstract

Introduction There are several reports on tracheoesophageal fistula formation and related morbidity and mortality in patients with lung cancer treated with chemoradiotherapy and bevacizumab. We draw attention to a recent patient in whom bronchoesophageal fistula and fatal hemoptysis developed after the first course of treatment of a pulmonary adenocarcinoma with platinum-based chemotherapy containing bevacizumab without radiotherapy.