Palladium(II)‐Catalyzed <i>ortho</i> Alkylation of Benzoic Acids with Alkyl Halides

Abstract

Outsmarting the competition: In the PdII-catalyzed reaction of benzoates with alkyl halides, an aryl CH bond is activated before the competitive alkylation of the carboxylate anion can takes place. The alkylation reaction was followed by an intramolecular lactonization to give broadly useful γ- and δ-benzolactones (see scheme). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.