Gingival Crevicular Fluid Levels of Monocyte Chemoattractant Protein‐1 and Tumor Necrosis Factor‐Alpha in Patients With Chronic and Aggressive Periodontitis

Abstract

These results suggest that MCP-1 could have an important role in the activation and recruitment of inflammatory and immune cells in periodontal diseases, and both AgP and CP patients may have the same pattern of MCP-1 expression. A strong positive correlation between the GCF levels of MCP-1 and TNF-alpha may account for the mechanism of amplification of inflammatory events in gingival inflammation.