BMJ Open · 2015 · 54 citations · 14 references
MedicineInternal MedicinePsychiatryDrug Utilization ReviewPain ManagementPain MedicineChronic DiseaseChronic PainMedication UsePharmacoepidemiologyPolypharmacy ConsiderationsAdult PrevalenceOutcome MeasuresPolypharmacy In Chronic DiseaseRetrospective Documentation ReviewRetrospective Record ReviewSelective Serotonin Reuptake Inhibitor UseSelective Serotonin-norepinephrine Reuptake Inhibitor TherapySerotonin-norepinephrine Reuptake Inhibitor Use
OBJECTIVES: The objective of this study was to evaluate the problem of multiple chronic conditions and polypharmacy in patients with fibromyalgia. DESIGN: Retrospective medical record review. SETTING: Olmsted County, Minnesota. PARTICIPANTS: 1111 adults with fibromyalgia. PRIMARY AND SECONDARY OUTCOME MEASURES: Number and type of chronic medical and psychiatric conditions, medication use. RESULTS: Medical record review demonstrated that greater than 50% of the sample had seven or more chronic conditions. Chronic joint pain/degenerative arthritis was the most frequent comorbidity (88.7%), followed by depression (75.1%), migraines/chronic headaches (62.4%) and anxiety (56.5%). Approximately, 40% of patients were taking three or more medications for symptoms of fibromyalgia. Sleep aids were the most commonly prescribed medications in our sample (33.3%) followed by selective serotonin reuptake inhibitors (28.7%), opioids (22.4%) and serotonin norepinephrine reuptake inhibitors (21.0%). CONCLUSIONS: The results of our study highlight the problem of multiple chronic conditions and high prevalence of polypharmacy in fibromyalgia. Clinicians who care for patients with fibromyalgia should take into consideration the presence of multiple chronic conditions when recommending medications.
14
The prevalence and characteristics of fibromyalgia in the general population
Frederick Wolfe, K. A. Ross, Janice Anderson et al. · Arthritis & Rheumatism · 1995 · 2.4K citations
Frederick Wolfe, Daniel J. Clauw, Mary‐Ann Fitzcharles et al. · The Journal of Rheumatology · 2011 · 1.5K citations · Full text
Jennifer L. St. Sauver, Brandon R. Grossardt, Barbara P. Yawn et al. · American Journal of Epidemiology · 2011 · 652 citations · Full text
Data Resource Profile: The Rochester Epidemiology Project (REP) medical records-linkage system
Jennifer L. St. Sauver, Brandon R. Grossardt, Barbara P. Yawn et al. · International Journal of Epidemiology · 2012 · 621 citations · Full text
Public Health, Biomedical Informatics, Electronic Health Records +12
Comorbidity of Fibromyalgia and Psychiatric Disorders
Lesley M. Arnold, James I. Hudson, Paul E. Keck et al. · The Journal of Clinical Psychiatry · 2006 · 384 citations