Single- Versus Multiple-Fraction Radiotherapy in Patients With Painful Bone Metastases: Cost-Utility Analysis Based on a Randomized Trial

Abstract

Compared with multiple-fraction radiotherapy, single-fraction radiotherapy provides equal palliation and quality of life and has lower medical and societal costs, at least in The Netherlands. Therefore, single-fraction radiotherapy should be considered as the palliative treatment of choice for cancer patients with painful bone metastases.