Two factor H-related proteins from the mouse: expression analysis and functional characterization

Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H

Matthew C. Pickering, H. Terence Cook, Joanna Warren et al. · Nature Genetics · 2002 · 506 citations

Medicine, Immunology, Pathology +17

Hereditary porcine membranoproliferative glomerulonephritis type II is caused by factor H deficiency.

J. H. Jansen, Tom Eirik Mollnes, Jan Hovdenes et al. · Journal of Clinical Investigation · 1995 · 211 citations · Full text

Medicine, Immunology, Pathology +17

Human Factor H-Related Protein 5 Has Cofactor Activity, Inhibits C3 Convertase Activity, Binds Heparin and C-Reactive Protein, and Associates with Lipoprotein

Jennifer L. McRae, Thomas G. Duthy, Kim Griggs et al. · The Journal of Immunology · 2005 · 155 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Functional properties of complement factor H‐related proteins FHR‐3 and FHR‐4: binding to the C3d region of C3b and differential regulation by heparin

Jens Hellwage, T. Sakari Jokiranta, Vesa Koistinen et al. · FEBS Letters · 1999 · 136 citations

Life Sciences, Biochemistry, Immunology +14

FHL-1/reconectin and factor H: two human complement regulators which are encoded by the same gene are differently expressed and regulated

Manuel A. Friese, Jens Hellwage, T. Sakari Jokiranta et al. · Molecular Immunology · 1999 · 111 citations

Life Sciences, Immunology, Molecular Biology +10