Estradiol Rates of Change in Relation to the Final Menstrual Period in a Population-Based Cohort of Women

Abstract

Population mean serum E2 levels were sustained until approximately 2 yr prior to the FMP. In the ensuing 4-yr period, E2 levels declined 67%. A secondary E2 decline, commencing about 6 yr after the FMP, was observed in nonobese but not obese women.