Concepedia

Intracellular metabolism of favipiravir (T-705) in uninfected and influenza A (H5N1) virus-infected cells

D. F. SMEE, Brett L. Hurst, Hiroyuki Egawa, Kohei Takahashi, Takumi Kadota, Yoshihiko Furuta

Journal of Antimicrobial Chemotherapy · 2009 · 98 citations · 11 references

DOIFull text

Open access

Abstract

The favourable intracellular metabolic properties of T-705 combined with its reduced cell-inhibitory properties make this compound an attractive candidate for treating human influenza virus infections.

References

11

A SIMPLE METHOD OF ESTIMATING FIFTY PER CENT ENDPOINTS12

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Mechanism of Action of T-705 against Influenza Virus

Yousuke Furuta, Kazumi Takahashi, Masako Kuno-Maekawa et al. · Antimicrobial Agents and Chemotherapy · 2005 · 539 citations · Full text

, , +10

In Vitro and In Vivo Activities of Anti-Influenza Virus Compound T-705

Yoshihiko Furuta, Kohei Takahashi, Yoshiko Fukuda et al. · Antimicrobial Agents and Chemotherapy · 2002 · 500 citations · Full text

Mechanism of Action of 1-β-D-Ribofuranosyl-1,2,4-Triazole-3-Carboxamide (Virazole), A New Broad-Spectrum Antiviral Agent

David Streeter, J. T. WITKOWSKI, G. P. Khare et al. · Proceedings of the National Academy of Sciences · 1973 · 478 citations · Full text

Inhibition of Influenza Virus Ribonucleic Acid Polymerase by Ribavirin Triphosphate

B. Eriksson, Erik Helgstrand, Nils Gunnar Johansson et al. · Antimicrobial Agents and Chemotherapy · 1977 · 255 citations · Full text