Ethyl Pyruvate Protects against Blood–Brain Barrier Damage and Improves Long‐term Neurological Outcomes in a Rat Model of Traumatic Brain Injury - Concepedia

Concepedia

Publication | Open Access

Ethyl Pyruvate Protects against Blood–Brain Barrier Damage and Improves Long‐term Neurological Outcomes in a Rat Model of Traumatic Brain Injury

DOI Full Paper Access

57

Citations

30

References

2014

Year

Hong Shi, Hailian Wang, Hongjian Pu, Yejie Shi, Jia Zhang, Wenting Zhang, Guohua Wang, Xiaoming Hu, Rehana K. Leak, Jun Chen,

CNS Neuroscience & Therapeutics

Abstract

Ethyl pyruvate confers long-term neuroprotection against TBI, possibly through breaking the vicious cycle among MMP-9-mediated BBB disruption, neuroinflammation, and long-lasting brain damage.

References

	Year	Citations

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