Tracheobronchial Calcification in Members of a Fixed Population Sample

Abstract

The Radiation Effects Research Foundation (formerly, Atomic Bomb Casualty Commission; ABCC) was established in April 1975 as a private non-profit Japanese Foundation, supported equally by the Government of Japan through the Ministry of Health and Welfare, and the Government of the United States through the National Academy of Sciences under contract with the United States Department of Energy. Accepted 4 December 1988. In a review of the chest radiographs of 1 152 consecutively examined subjects, 10 cases (0.87%) of extensive tracheobronchial calcification were identified. In addition, 51 subjects having this coded diagnosis were identified among 11758 members of a fixed population sample. Sixty of these 61 subjects were women. Tracheobronchial calcification usually appeared after the age of 60. The subjects' clinical and other radiologic diagnoses were reviewed and tracheobronchial calcification appeared to have no clinical significance. Histologic findings in autopsied cases showed the calcifications and ossificiations to be in the cartilaginous rings themselves. However, the reason for the overwhelming prevalence of this entity in women remains to be resolved.