A computational fluid dynamics study on geometrical influence of the aorta on haemodynamics

Abstract

The aorta with an irregular contour and large degree of curvature at its arch favours the development of the intra-aortic secondary flow that subsequently relates to the pathogenesis of atheroma. The present study identifies the general trend of haemodynamic behaviours associated with various local geometrical features. Combining the knowledge of the correlation between haemodynamics and the underlying risks in the development of cardiovascular diseases, our study hopes to provide a better understanding of the relationship between aortic morphology and developing pathobiology of cardiovascular diseases. As such, early medical planning as well as surgical interventions can be designed to retard or prevent the development of cardiovascular diseases.