Bioinformation · 2009 · 60 citations · 0 references
Life SciencesGeneticsMolecular GeneticsEpigeneticsEpigenomicsGenomicsCancer EpigeneticsCancer EpigenomicsCancer GenomicsCpg IslandsEpigenetic Alterations In CancerEpigenetic Regulation In CancerCancer Structural Variant AnalysisCpg Island Cancer EpigeneticsCpg Island HypermethylationCpg Island HypomethylationCpg Island MethylationCpg Island Methylation PatternsOncogene HypomethylationStructural Patterns
Giving coding region structural features a role in the hypomethylation of specific genes, the occurrence of G+C content, CpG islands, repeat and retrotransposable elements in demethylated genes related to cancer has been evaluated. A comparative analysis among different cancer types has also been performed. In this work, the inter-cancer coding region features comparative analysis carried out, show insights into what structural trends/patterns are present in the studied cancers.