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EFFECTS OF FAT-MOBILIZING EXTRACT FROM HUMAN URINE ON METABOLISM OF GLUCOSE IN RAT ADIPOSE TISSUE<sup>1</sup>
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1961
Year
Metabolic DisorderSmall PeptideObesityMetabolic SyndromeBody CompositionFatty AcidsMetabolic SignalingMetabolic StateHuman MetabolismAdipose Tissue MetabolismHealth SciencesBiochemistryAdipose TissueMetabolomicsEndocrinologyPharmacologyPhysiologyMetabolic RegulationMetabolismMedicineLipid Synthesis
Fat-mobilizing substance (PMS), a small peptide isolated from urine of carbohydrate deprived humans, alters carbohydrate metabolism in isolated epididymal adipose tissue in a pattern similar to that of epinephrine and preparations of ACTH and growth hormone. It is inferred that FMS primarily mobilizes fatty acids from adipose tissue by directly augmenting the lipolytic reaction.