PheP, a Putative Amino Acid Permease of <i>Staphylococcus aureus</i> , Contributes to Survival In Vivo and during Starvation

Malcolm J. Horsburgh, Michael Wiltshire, Howard Crossley, Eileen Ingham, Simon J. Foster

Infection and Immunity · 2004 · 18 citations · 22 references

DOIFull text

Open access

Concepts

Abstract

PheP, a putative amino acid permease in Staphylococcus aureus, contributes to starvation survival under glucose-limiting conditions and virulence. A pheP mutation led to poor growth after microaerobic or anaerobic incubation on pig serum agar, which was recovered by phenylalanine addition. Genetic complementation of pheP restored growth and starvation survival.

References

22