Endocrine Metabolic & Immune Disorders - Drug Targets · 2015 · 12 citations · 0 references
Veterinary MedicineImmunologyPathologyImmunopathologyInflammationInnate ImmunityAcute InflammationCytokine BiologyCytokine-mediated PathologyInflammatory Cell ResponsesInflammatory PathologyInflammatory SignalingInflammatory Cytokine ProductionInflammatory Cytokine SecretionInterleukin-1 Family CytokinesInterleukin-1 Mediated InflammationInterleukin-1-mediated InflammationInterleukin-mediated Inflammation
Inflammation is a protective response to eliminate cytotoxic agents and pathogens. Various factors are thought to be involved in the pathological changes in tissues caused by inflammation. Interleukin 1, an inflammatory cytokine, is thought to have diverse physiological functions and to play an important role in inflammatory disease. In this review, we discuss interleukin-1 as a target of inflammatory disease. Keywords: Infectious diseases, inflammasome, inflammation, interleukin-1β, receptors, tissue.