The affinity of chlorhexidine for hydroxyapatite and salivary mucins

Abstract

This study indicates that chlorhexidine gluconate adsorbs to hydroxyapatite, tooth surfaces and salivary mucins and that the adsorbed chlorhexidine is released when the concentration in the environment is low. The possible formation of reservoirs of chlorhexidine on the tooth surface in vivo from which chlorhexidine is slowly released could, therefore, prevent bacterial colonization and the development of dental plaque.