Serum Apolipoprotein A-I and Large High-Density Lipoprotein Particles Are Positively Correlated with FEV ₁ in Atopic Asthma

Abstract

In subjects with atopy and asthma, serum levels of apoA-I and large HDLNMR particles are positively correlated with FEV1, whereas serum triglycerides, LDL cholesterol, and apoB are associated with more severe airflow obstruction. These results may facilitate future studies to assess whether apoA-I and large HDLNMR particles can reduce airflow obstruction and disease severity in asthma.