Journal of Medical Microbiology · 1986 · 14 citations · 2 references
Life SciencesInfectious DiseasesMicrobiologyFood MicrobiologyMicrobial EcologyMicrobial PathogenesisBacterial SporesBacterial SporulationBacterial ToxinsMicrobial Toxins In FoodSpore BiologyToxin ProductionBacterial Toxin BiologyBacterial Toxin ProductionClostridial SporesClostridial SporulationFoodborne Toxin ProductionMicrobial Toxin ProductionSpore ProductionToxin-producing Bacteria
The kinetics of spore production by Clostridium difficile were not paralleled by release of C. difficile toxin A in vitro. Toxin A was not found to be associated with either purified whole spores or spore coats. Residual traces of toxin A detected in spore contents were almost certainly derived from contaminating vegetative cell debris. Thus, toxin A is unlikely to be a spore constituent or associated with sporogenesis.
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