Immunoglobulin E to Staphylococcal and Streptococcal Toxins in Patients with Chronic Sinusitis/Nasal Polyposis

Abstract

A significantly greater proportion of CS/NP patients had IgE to staphylococcal or streptococcal toxins. Evidence of IgE antibodies directed against staphylococcal and streptococcal toxins in the sera of patients with CS/NP suggests a potential role of these toxins with established superantigen effects in the pathogenesis of CS/NP.