Chiral Hypervalent Iodine Reagents in Asymmetric Reactions

Abstract

All hyper: Recent advances in the area of chiral hypervalent iodine reagents, notably by the groups of Kita, Ishihara, and Fujita, enable some oxidative transformations to be conducted in an enantioselective manner and with asymmetric inductions in the range of 86–95 % ee (see scheme, Mes=mesityl). This contribution highlights representative reactions, reagent/catalyst design, and mechanistic aspects of the reported transformations.