Association Between Val66Met Brain‐Derived Neurotrophic Factor (BDNF) Gene Polymorphism and Post‐Treatment Relapse in Alcohol Dependence

Abstract

The Val66Met BDNF gene polymorphism was associated with a higher risk and earlier occurrence of relapse among patients treated for alcohol dependence. The study suggests a relationship between genetic markers and treatment outcomes in alcohol dependence. Because a large number of statistical tests were conducted for this study and the literature on genetics and relapse is so novel, the results should be considered as hypothesis generating and need to be replicated in independent studies.