Distinguishing DNA by Analog‐to‐Digital‐like Conversion by Using Optofluidic Lasers

Abstract

Laser precision: A highly sensitive technique based on laser emission for differentiating a target DNA strand from strands that contain single base mismatches has been developed. Laser emission is used to amplify the small difference in signals that are generated by the different strands after hybridization with a molecular beacon (MB, see picture) in a conversion that is similar to analog-to-digital. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.