SPARC is expressed in scars of the Tenon's capsule and mediates scarring properties of human Tenon's fibroblasts in vitro. - Concepedia

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SPARC is expressed in scars of the Tenon's capsule and mediates scarring properties of human Tenon's fibroblasts in vitro.

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2011

Year

Rudolf Fuchshofer, Ulrike B. Kottler, Anne V. Ohlmann, Ursula Schlötzer‐Schrehardt, Anselm Jünemann, Friedrich E. Kruse, Andreas Ohlmann

Abstract

Our data provide evidence that SPARC contributes to excessive wound healing and scar formation in human Tenon's capsules after filtration surgery and may thus represent a novel target for anti-fibrotic strategies.

References

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