Publication | Closed Access
Multicomponent One‐pot Diastereoselective Synthesis of Biologically Important Scaffold under Microwaves
27
Citations
32
References
2006
Year
Experimental SynthesisChemical EngineeringDiversity Oriented SynthesisBioorganic ChemistryEngineeringImportant SpiroNatural SciencesDiversity-oriented SynthesisOrganic ChemistrySynthesis MethodEthyl Cyanoacetate 2Natural Product SynthesisMicrowave SynthesisSynthetic ChemistryBiomolecular EngineeringBiologically Important ScaffoldAvailable 1
Abstract A simple and fast three‐component diastereoselective synthesis of biologically important spiro scaffold 4 was carried out in reasonable purity starting from readily available 1 H ‐indole‐2,3‐dione 1 , ethyl cyanoacetate 2 and 4‐hydroxycoumarin 3 under microwave in high yield (88%–92%) and short time.
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