Treatment with anti-TNF monoclonal antibody (c5N) reduces the extent of induced endometriosis in the baboon

Abstract

In baboons with induced endometriosis, anti-TNF-mAb (c5N) treatment significantly reduced the extent of endometriosis, mainly due to reducing both the number and surface area of red lesions. These findings suggest that anti-TNF-mAb therapy may have therapeutic potential for active peritoneal endometriosis.