Concepedia

Enantioselective radical addition reactions to the CN bond utilizing chiral quaternary ammonium salts of hypophosphorous acid in aqueous media

Dae Hyan Cho, Doo Ok Jang

Chemical Communications · 2006 · 56 citations · 25 references

DOI

Concepts

Abstract

An enantioselective addition of alkyl radicals to glyoxylate oxime ether mediated by Cinchona alkaloid derived chiral ammonium salts of hypophosphorous acid, QP and QDP, has been developed.

References

25

The Enantioselective Synthesis of α-Amino Acids by Phase-Transfer Catalysis with Achiral Schiff Base Esters

Martin O’Donnell · Accounts of Chemical Research · 2004 · 760 citations

, , +14

Asymmetric Phase-Transfer Catalysis Utilizing Chiral Quaternary Ammonium Salts:  Asymmetric Alkylation of Glycine Imines

Barry Lygo, Benjamin I. Andrews · Accounts of Chemical Research · 2004 · 548 citations

, , +14

Enantioselective Free Radical Reactions

Mukund P. Sibi, Ned A. Porter · Accounts of Chemical Research · 1998 · 284 citations

, , +6

The invention of radical reactions. Part 32. Radical deoxygenations, dehalogenations, and deaminations with dialkyl phosphites and hypophosphorous acid as hydrogen sources

Derek H. R. Barton, Doo Ok Jang, Joseph Cs. Jászberényi · The Journal of Organic Chemistry · 1993 · 167 citations

, , +7

Hypophosphorous acid and its salts: New reagents for radical chain deoxygenation, dehalogenation and deamination

D. H. R. BARTON, Doo Ok Jang, Joseph Cs. Jászberényi · Tetrahedron Letters · 1992 · 145 citations

, , +6