Archives of Internal Medicine · 1979 · 170 citations · 19 references
Veterinary MedicineInfectious DiseasesMicrobiologyMicrobial PathogenesisPulmonologySepsisAcute Lung InjuryAcute Respiratory Distress SyndromeCoagulation AbnormalitiesComplications Of SepsisSepsis PathophysiologySeptic ShockAdult Respiratory Distress SyndromeGram-negative BacteremiaGram-negative Bloodstream InfectionSepsis-associated Acute Respiratory Distress SyndromeSepsis-associated Respiratory FailureSepsis-induced Acute Respiratory Distress Syndrome PrognosisSepsis-induced CoagulopathySepsis-related Respiratory Distress
Twenty cases of the adult respiratory distress syndrome (ARDS) in 86 cases of Gram-negative bacteremia were identified. Features of Gram-negative bacteremia associated with the development of ARDS included a history of cardiac disease, hypotension, and thrombocytopenia. The mortality of patients with and without ARDS was 90% and 55%, respectively. The association of hypotension and thrombocytopenia with the subsequent development of ARDS suggests the possible role of endotoxin-induced coagulopathy in this complication.
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ACUTE RESPIRATORY DISTRESS IN ADULTS
D G Ashbaugh, D. Boyd Bigelow, ThomasL. Petty · The Lancet · 1967 · 4.3K citations
The Adult Respiratory Distress Syndrome
Thomas L. Petty, David G. Ashbaugh · CHEST Journal · 1971 · 785 citations