Heterogeneous Patterns of <b> <i>FLT3</i> </b> Asp835 Mutations in Relapsed <b> <i>de Novo</i> </b> Acute Myeloid Leukemia

Abstract

The present study showed that patients with AML had heterogeneous patterns of FLT3 Asp(835) mutations, either acquisition or loss of the mutations at relapse. Asp(835) mutant clone may develop as a secondary event in a subset of patients with AML.