Aerobic Alcohol Oxidation Coupled to Palladium‐Catalyzed Alkene Hydroarylation with Boronic Esters

Abstract

An oxidation exercise: An aerobic alcohol oxidation coupled with a regioselective palladium-catalyzed reductive functionalization of styrenes and arylboronic esters has been developed (see scheme). The mechanism is thought to proceed by initial oxidation of the solvent to generate a PdII-hydride species, which subsequently reacts with the alkene and arylboronic ester to ultimately generate a new CC bond. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z705317_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.