Ex vivo HR-MAS magnetic resonance spectroscopy of normal and malignant human renal tissues.

Abstract

This paper demonstrates that ex vivo HR-MAS MRS is a viable and powerful means of probing for molecular information in human normal and tumoral renal tissues. This research will constitute the basis for a biochemical classification of renal neoplastic pathologies, especially for RCCs, which can be thus evaluated by in vivo MRS for clinical purposes. Moreover, these data may contribute to a better knowledge of the molecular processes for the basis of the onset of renal carcinogenesis.