Oral retinoic acid metabolism blocking agent Rambazole^TMfor plaque psoriasis: an immunohistochemical study

Abstract

Clinical efficacy of rambazole is primarily the result of restoring proliferation (Ki67) and differentiation (K10) of epidermal keratinocytes. Secondly, relevant T-cell subsets and cells expressing NK-receptors showed nonsignificant reductions after 8 weeks of treatment with rambazole.