Using Optogenetics to Interrogate the Dynamic Control of Signal Transmission by the Ras/Erk Module

Enzymatic assembly of DNA molecules up to several hundred kilobases

Daniel G. Gibson, Lei Young, Ray-Yuan Chuang et al. · Nature Methods · 2009 · 10.9K citations

Life Sciences, Biochemistry, Molecular Biology +16

Millisecond-timescale, genetically targeted optical control of neural activity

Edward S. Boyden, Feng Zhang, Ernst Bamberg et al. · Nature Neuroscience · 2005 · 4.9K citations

Life Sciences, Neurobiology, Neuroscience +12

Structure and function of the feed-forward loop network motif

Shmoolik Mangan, Uri Alon · Proceedings of the National Academy of Sciences · 2003 · 1.9K citations · Full text

Life Sciences, Molecular Biology, Gene Expression +14

Optogenetic stimulation of a hippocampal engram activates fear memory recall

Xu Liu, Steve Ramirez, Petti T. Pang et al. · Nature · 2012 · 1.8K citations

Life Sciences, Neurobiology, Neuroscience +16

Rapid blue-light–mediated induction of protein interactions in living cells

Matthew J. Kennedy, Robert M. Hughes, Leslie A Peteya et al. · Nature Methods · 2010 · 1.2K citations

Natural Sciences, Biophysics, Cell Biology +11